Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.86 |
| ▸ | HTT | P42858 | 4/20 | 0.86 |
| ▸ | NPC1 | O15118 | 1/20 | 0.86 |
| ▸ | RAB9A | P51151 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | BMP1 | P13497 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474346 | 0.93 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL23057256 | 0.89 | LMNA (0.73) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL11182312 | 0.86 | LMNA (1.00) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL1471666 | 0.82 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL11547843 | 0.81 | HTT (0.58) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL10948438 | 0.81 | LMNA (0.76) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL4204765 | 0.80 | LMNA (0.76) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL10950108 | 0.80 | LMNA (0.85) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29285860 | 0.79 | LMNA (0.73) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL28109018 | 0.79 | HTT (0.73) | LMNASMN1; SMN2HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | claimed |
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |