SCHEMBL11547843

SCHEMBL11547843

CS(=O)(=O)c1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.58
ALDH1A1 P00352 4/20 0.58
SMN1; SMN2 Q16637 6/20 0.58
LMNA P02545 5/20 0.58
ENPP2 Q13822 2/20 0.54
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TP53 P04637 1/20 0.52
MAPT P10636 1/20 0.52
TSHR P16473 1/20 0.52
XBP1 P17861 1/20 0.52
MAPK1 P28482 1/20 0.52
MDM2 Q00987 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PTGS2 P35354 3/20 0.52
SOS1 Q07889 2/20 0.50
POLB P06746 1/20 0.50
PTGS1 P23219 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941654 0.93 PTGS2 (0.56) HTTALDH1A1SMN1; SMN2LMNAENPP2
SCHEMBL13814624 0.91 HTT (0.63) HTTALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL2758531 0.91 HTT (0.63) HTTALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL8005674 0.91 PKM (0.61) NPC1RAB9APTGS2PTGS1
SCHEMBL7359540 0.91 SOS1 (0.64) HTTSMN1; SMN2LMNATSHRPTGS2
SCHEMBL7363201 0.89 PTGS2 (0.56) HTTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL3913682 0.89 HTT (0.48) HTTALDH1A1SMN1; SMN2LMNAENPP2
SCHEMBL178009 0.89 ALDH1A1 (0.58) HTTALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL7937506 0.89 ENPP2 (0.75) HTTALDH1A1SMN1; SMN2LMNAENPP2
SCHEMBL10950514 0.89 PTGS2 (0.54) HTTALDH1A1SMN1; SMN2LMNAENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322985-A1 CURABLE RESIN COMPOSITION AND CEMENTED LENS FUJIFILM CORPORATION (JP) 2023-10-12 US disclosed
WO-2019153135-A1 POLY(ARYL ETHER SULFONE)-ETHER IMIDE COPOLYMER AND PREPARATION METHOD THEREFOR 江门市优巨新材料有限公司 2019-08-15 WO disclosed
US-20180154671-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE-MAKING METHOD FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
US-20170329225-A1 PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed
US-20170173938-A1 PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND FUJIFILM CORPORATION (JP) 2017-06-22 US disclosed
US-20170017153-A1 PHOTOSENSITIVE RESIN COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2017-01-19 US disclosed
US-8648094-B2 IAP BIR domain binding compounds PHARMASCIENCE, INC. (CA) 2014-02-11 US disclosed
US-20090170840-A1 NS1 protein inhibitors THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-07-02 US disclosed
US-7244544-B2 Oxime derivatives and the use thereof as latent acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-17 US disclosed
US-7244544-B2 Oxime derivatives and the use thereof as latent acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-17 US disclosed
US-4137273-A INSECTICIDES, CHEMICAL INTERMEDIATES ZOECON CORPORATION (US) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170840-A1 NS1 protein inhibitors MAVS, SERPINB1, SPINT2 HTT 1036/4885ALDH1A1 3348/4885SMN1; SMN2 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.