Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941136 | 0.97 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AGFERALDH1A1 | |
| SCHEMBL10949232 | 0.94 | KDM4E (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL10943838 | 0.91 | KDM4E (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL10943646 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL10942241 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL9679487 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL10941375 | 0.81 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AGFERALDH1A1 | |
| SCHEMBL10944755 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AGFERALDH1A1 | |
| SCHEMBL10943648 | 0.81 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AGFERALDH1A1 | |
| SCHEMBL10946025 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |