Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945207 | 0.97 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL10947113 | 0.94 | IMPDH2 (0.49) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL10946433 | 0.91 | IMPDH2 (0.46) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL10942847 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL10947125 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL9679951 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2NPC1KDM4EALDH1A1HPGD | |
| SCHEMBL10943648 | 0.81 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AGFERKDM4E | |
| SCHEMBL10945982 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL10941375 | 0.81 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AGFERHSD17B10 | |
| SCHEMBL14582452 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2NPC1RAB9AGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |