Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031155 | 0.91 | CYP2C19 (0.64) | SLC6A3SLC6A2SLC6A4TSHRCYP2C19 | |
| SCHEMBL10941283 | 0.89 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4CYP2C19CNR2 | |
| SCHEMBL10473223 | 0.88 | TSHR (0.75) | SLC6A3SLC6A2SLC6A4TSHRCYP2C19 | |
| SCHEMBL14980578 | 0.84 | TSHR (0.62) | SLC6A3SLC6A2SLC6A4TSHRCYP2C19 | |
| SCHEMBL10474254 | 0.84 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4TSHRCYP2C19 | |
| SCHEMBL43183 | 0.84 | TSHR (0.74) | SLC6A3TSHRCYP2C19CNR2CYP2D6 | |
| SCHEMBL10982514 | 0.83 | NR1H3 (0.53) | SLC6A3SLC6A2SLC6A4TSHRCYP2D6 | |
| SCHEMBL10939765 | 0.83 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL2139953 | 0.81 | TSHR (0.71) | SLC6A3TSHRCYP2C19CNR2CYP2D6 | |
| SCHEMBL355040 | 0.81 | TSHR (0.71) | SLC6A3TSHRCYP2C19CNR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58054346-A | — | — | None | — | — | JP | disclosed |
| US-4500623-A | Photoconductive compositions comprising an organic photoconductor and a thioamide compound and electrophotographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4499167-A | Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4447515-A | DIACYLAMINE COMPOUND ADDED | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
| US-4387149-A | CATIONIC DYES; STABILITY; COPYING | MITSUBISHI PAPER MILLS, LTD. (JP) | 1983-06-07 | — | — | US | disclosed |
| JP-S5854346-A | ELECTROPHOTOGRAPHIC RECEPTOR | MITSUBISHI PAPER MILLS LTD | 1983-03-31 | — | — | JP | disclosed |
| US-3963779-A | 1,1-BIS(N,N-DIPHENYL-ALKYL-AMINO-PHENYL)-ALKANE | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-06-15 | — | — | US | disclosed |