SCHEMBL43183

SCHEMBL43183

c1ccc(CN(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.74
CYP2C19 P33261 1/20 0.71
CYP2D6 P10635 2/20 0.58
TAAR1 Q96RJ0 2/20 0.58
LMNA P02545 2/20 0.58
CYP1A2 P05177 1/20 0.58
HTR1A P08908 1/20 0.58
ADRA2A P08913 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
PDE6A P16499 1/20 0.58
ADRA2C P18825 1/20 0.58
MC4R P32245 1/20 0.58
ADRA1A P35348 1/20 0.58
HRH1 P35367 1/20 0.58
OPRM1 P35372 1/20 0.58
DRD3 P35462 1/20 0.58
MC3R P41968 1/20 0.58
SLC6A3 Q01959 1/20 0.58
KMT2A Q03164 1/20 0.58
PDE4D Q08499 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355040 0.97 TSHR (0.71) TSHRCYP2C19CYP2D6TAAR1LMNA
Hydrochloric Acid SCHEMBL2139953 0.97 TSHR (0.71) TSHRCYP2C19CYP2D6TAAR1LMNA
Nitrogen SCHEMBL4599425 0.95 TSHR (0.68) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL2960872 0.94 CYP2C19 (0.78) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL2011193 0.87 CYP2C19 (0.69) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL7154167 0.87 CYP2C19 (0.69) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL10974928 0.87 CRHBP (0.68) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL15456984 0.87 CYP2C19 (0.88) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL7354472 0.85 TSHR (0.63) TSHRCYP2C19CYP2D6TAAR1LMNA
SCHEMBL7354477 0.85 TSHR (0.63) TSHRCYP2C19CYP2D6TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US claimed
US-20240355476-A1 METHODS AND COMPOSITIONS RELATED TO TRIPLE-NEGATIVE BREAST CANCER THE UNIVERSITY OF CHICAGO (US) 2024-10-24 US claimed
CN-118725604-A Alkali-resistant disperse dye and synthetic method and application thereof 绍兴文理学院 2024-10-01 CN claimed
CN-113970978-B Manufacturing method of large-scale touch sensing pattern 洋华光电股份有限公司 2023-11-24 CN claimed
CN-113970978-A Manufacturing method of large touch sensing pattern 洋华光电股份有限公司 2022-01-25 CN claimed
US-11215923-B1 Method for manufacturing large-scale touch sensing pattern YOUNG FAST OPTOELECTRONICS CO., LTD. (TW) 2022-01-04 US claimed
CN-112409412-A Improved synthesis process of antihypertensive efonidipine hydrochloride 重庆化工职业学院 2021-02-26 CN claimed
CN-111533875-A Preparation method of cationic waterborne polyurethane, leather bottom sealing resin and leather coating 合肥科天水性科技有限责任公司 2020-08-14 CN claimed
EP-2115533-B1 PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROMENES RODENSTOCK GMBH (DE) 2010-06-30 EP claimed
CN-100382796-C Methods and compositions for providing glutamine ABBOTT LAB (US) 2008-04-23 CN claimed
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO claimed
EP-1215745-A1 NON-AQUEOUS ELECTROLYTE SECONDARY CELL AND DEVICE USING THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-06-19 EP claimed
CN-1349672-A Non-aqueous electrolyte secondary cell and device using the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-05-15 CN claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-4368254-A AROMATIC AMINE CHROMOGEN VANNIKOV ANATOLY V (SU) 1983-01-11 US claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-4224416-A Degradable plastic composition containing amine OWENS-ILLINOIS, INC. (US) 1980-09-23 US claimed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US claimed
US-4101720-A Degradable plastic OWENS-ILLINOIS, INC. (US) 1978-07-18 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552956-B2 Photopolymerizable type dental surface coating composition CDH1, DCLRE1A, ITGA1 TSHR 3987/4885CYP2C19 3191/4885CYP2D6 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.