SCHEMBL10939765

SCHEMBL10939765

Clc1ccc(CN(Cc2ccc(Cl)cc2)c2ccc(Cc3ccc(N(Cc4ccc(Cl)cc4)Cc4ccc(Cl)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CNR2 P34972 10/20 0.45
CNR1 P21554 6/20 0.45
ALDH1A1 P00352 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2C19 P33261 1/20 0.44
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
REN P00797 2/20 0.42
PYCR1 P32322 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941283 0.93 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL3031155 0.83 CYP2C19 (0.64) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL10945992 0.83 SLC6A3 (0.63) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL10763738 0.80 CYP2C19 (0.67) SLC6A3CNR2ALDH1A1CYP2C19CYP3A4
SCHEMBL10986600 0.79 ALDH1A1 (0.42) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL10951888 0.79 CNR2 (0.50) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL10471669 0.79 CNR2 (0.43) SLC6A2SLC6A4SLC6A3CNR2CNR1
SCHEMBL11775688 0.79 CNR2 (0.59) CNR2CNR1ALDH1A1TDP1PYCR1
SCHEMBL1106684 0.78 IDO1 (0.58) SLC6A2SLC6A4SLC6A3ALDH1A1CYP3A4
SCHEMBL2759051 0.78 TAAR1 (0.47) SLC6A4CNR2CNR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4500623-A Photoconductive compositions comprising an organic photoconductor and a thioamide compound and electrophotographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
US-4499167-A Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-12 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed