SCHEMBL109469

SCHEMBL109469

O=c1[nH]c(=O)n(CC(O)O)c(=O)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13413739 0.80 MMP9 (0.36) APEX1
SCHEMBL29063539 0.79 CHRM1 (0.36)
SCHEMBL28512835 0.77 APEX1 (0.39) APEX1
SCHEMBL20865055 0.76 ALDH1A1 (0.46)
SCHEMBL11698657 0.76 TYMP (0.30)
SCHEMBL10602755 0.74 APEX1 (0.31) APEX1
SCHEMBL28673531 0.73 KDM4E (0.37)
SCHEMBL4344704 0.71
SCHEMBL28793934 0.71
SCHEMBL29252281 0.71 DAO (0.39) APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865904-A Preparation method of tris (hydroxyethyl) isocyanurate 浙江皇马科技股份有限公司 2024-04-12 CN disclosed
US-20240117215-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2024-04-11 US disclosed
CN-116583547-A Multifunctional hydrazide crosslinking agents PPG工业俄亥俄公司 2023-08-11 CN disclosed
US-20230220219-A1 COMPOSITIONS CONTAINING THERMALLY CONDUCTIVE FILLERS PPG INDUSTRIES OHIO, INC. (US) 2023-07-13 US disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
CN-115702189-A Composition containing thermally conductive filler PPG工业俄亥俄公司 2023-02-14 CN disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
US-11149107-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-10-19 US disclosed
WO-2007073474-A1 IMPACT RESISTANT POLYURETHANE AND POLY(UREAURETHANE) ARTICLES AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-28 WO disclosed
US-20070149749-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US disclosed
US-20070149748-A1 Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US disclosed
US-20070148471-A1 Impact resistant polyurethane and poly(ureaurethane) articles and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US disclosed
WO-2007070627-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-21 WO disclosed
US-6130270-A FOR OPTICAL PARTS SUCH AS LENSES, OPTICAL DISKS, PRISMS, LENS SHEETS WHICH ARE MOLDED BY POLYMERIZATION IN DIES; FOR USE AS SURFACE COATING MATERIAL OF PLASTIC FILM SUBSTRATES USED FOR OPTICAL MATERIALS SUCH AS FOR LIQUID CRYSTAL DISPLAY ELEMENTS DSM N.V. (NL) 2000-10-10 US disclosed
EP-0909399-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1999-04-21 EP disclosed
US-5719281-A FROM CYANURIC ACID AND AN ALIPHATIC EPOXIDE IN PRESENCE OF AN ORGANIC PHOSPHORUS COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO disclosed
EP-0274306-A2 Process for the preparation of cyanuric-acid dichlorohydrines, and their trisubstituted derivatives ELF ATOCHEM S.A. (FR) 1988-07-13 EP disclosed