SCHEMBL10947962

SCHEMBL10947962

CCN1C(=O)C(=C/C=C/Nc2ccccc2)C(=O)N(CC)C1=S

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.53
▸ MAPT P10636 6/20 0.53
▸ MEN1 O00255 6/20 0.53
▸ KMT2A Q03164 6/20 0.53
▸ MDM2 Q00987 3/20 0.53
▸ HTT P42858 3/20 0.53
▸ POLB P06746 2/20 0.53
▸ HPGD P15428 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ THRB P10828 1/20 0.53
▸ KDM4C Q9H3R0 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ TNFRSF1A P19438 5/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ LMNA P02545 2/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ENPP3 O14638 1/20 0.43
▸ NR1H2 P55055 1/20 0.39
▸ NR1H3 Q13133 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10947969 1.00 ALDH1A1 (0.53) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL11640059 0.83 TNFRSF1A (0.48) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL14712965 0.79 MAPT (0.64) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL11422979 0.78 CRHBP (0.63) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL10036013 0.78 CRHBP (0.63) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL19240095 0.76 APP (0.43) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL11149658 0.73 TNFRSF1A (0.56) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL14712874 0.73 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL14712964 0.72 MAPT (0.61) ALDH1A1MAPTMEN1KMT2AMDM2
SCHEMBL14712993 0.71 MEN1 (0.57) ALDH1A1MAPTMEN1KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4520098-A CONTAINING FINE IODIDE SILVER HALIDE PARTICLES IN CONCENTRATION CAPABLE OF BEING DISSOLVED OUT EASTMAN KODAK COMPANY (US) 1985-05-28 — — US disclosed
US-4490458-A Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (US) 1984-12-25 — — US disclosed
US-4459353-A Gamma phase silver iodide emulsions, photographic elements containing these emulsions, and processes for their use EASTMAN KODAK COMPANY (US) 1984-07-10 — — US disclosed
US-4439520-A Sensitized high aspect ratio silver halide emulsions and photographic elements EASTMAN KODAK COMPANY (US) 1984-03-27 — — US disclosed
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