Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551505 | 0.84 | MAPT (0.60) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL5580657 | 0.83 | MAPT (0.55) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL2349955 | 0.82 | MAPT (0.61) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL11741381 | 0.79 | MAPT (0.56) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL948318 | 0.79 | MAPT (0.59) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL10951960 | 0.78 | MAPT (0.55) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL10951505 | 0.77 | MAPT (0.54) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL14398351 | 0.77 | CYP2C19 (0.50) | MAPTHTTLMNANPSR1L3MBTL1 | |
| SCHEMBL28557944 | 0.77 | ALDH1A1 (0.58) | MAPTHTTLMNANPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL22346017 | 0.77 | MAPT (0.58) | MAPTHTTLMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552890-A | Plant phytopathogenic fungicidal agents based on maleimide | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | claimed |
| US-4552890-A | Plant phytopathogenic fungicidal agents based on maleimide | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |