Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.58 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 known ✓ | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 known ✓ | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 known ✓ | Q9UQL6 | 1/20 | 0.57 |
| ▸ | KCNK3 known ✓ | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 known ✓ | Q9NPC2 | 1/20 | 0.55 |
| ▸ | GRIN2D known ✓ | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B known ✓ | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 known ✓ | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B known ✓ | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C known ✓ | Q14957 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948318 | 0.98 | MAPT (0.59) | MAPTALDH1A1GAAPOLBHDAC3 | |
| Acrylic Acid SCHEMBL3955124 | 0.87 | MAPT (0.52) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL2022897 | 0.86 | POLB (0.53) | MAPTALDH1A1GAAPOLBHDAC3 | |
| Hydrochloric Acid SCHEMBL28825350 | 0.86 | MAPT (0.61) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL9717979 | 0.85 | HTT (0.72) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL2349955 | 0.85 | MAPT (0.61) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL4622869 | 0.85 | L3MBTL1 (0.56) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL29580443 | 0.85 | HTT (0.72) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL21551505 | 0.84 | MAPT (0.60) | MAPTALDH1A1GAAPOLBHDAC3 | |
| SCHEMBL2019462 | 0.83 | POLB (0.58) | MAPTALDH1A1GAAPOLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678626-A1 | LONG-CHAIN ALKENYLOXY-SUBSTITUTED BENZOYL DERIVATIVE AND OLIGONUCLEOTIDE SYNTHESIS METHOD USING SAME | Spera Pharma, Inc. (JP) | 2026-01-14 | — | — | EP | disclosed |
| US-12509484-B2 | Method of producing nucleic acid compound, and nucleic acid compound | FUJIFILM CORPORATION (JP) | 2025-12-30 | — | — | US | disclosed |
| WO-2024185775-A1 | LONG-CHAIN ALKENYLOXY–SUBSTITUTED BENZOYL DERIVATIVE AND OLIGONUCLEOTIDE SYNTHESIS METHOD USING SAME | スペラファーマ株式会社 | 2024-09-12 | — | — | WO | disclosed |
| WO-2022220019-A1 | LONG-CHAIN DNA SYNTHESIS USING NON-NATURAL BASE | 国立大学法人東京工業大学 | 2022-10-20 | — | — | WO | disclosed |
| US-20220259255-A1 | METHOD OF PRODUCING NUCLEIC ACID COMPOUND, AND NUCLEIC ACID COMPOUND | FUJIFILM CORPORATION (JP) | 2022-08-18 | — | — | US | disclosed |
| WO-2022172994-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | 味の素株式会社 | 2022-08-18 | — | — | WO | disclosed |
| EP-4006045-A1 | NUCLEIC ACID COMPOUND MANUFACTURING METHOD AND NUCLEIC ACID COMPOUND | FUJIFILM Corporation (JP) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021039935-A1 | NUCLEIC ACID COMPOUND MANUFACTURING METHOD AND NUCLEIC ACID COMPOUND | 富士フイルム株式会社 | 2021-03-04 | — | — | WO | disclosed |
| WO-2020196890-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE HAVING PHOSPHOROTHIOATE SITE | 味の素株式会社 | 2020-10-01 | — | — | WO | disclosed |
| WO-2020166705-A1 | PRODUCTION METHOD FOR OLIGONUCLEOTIDES | 味の素株式会社 | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259255-A1 | METHOD OF PRODUCING NUCLEIC ACID COMPOUND, AND NUCLEIC ACID COMPOUND | XRN2, RNASEH1, NSUN2 | GAA 4572/4885HDAC3 849/4885HDAC4 1297/4885 |
| US-12509484-B2 | Method of producing nucleic acid compound, and nucleic acid compound | NSUN2, RNASEH1, XRN2 | GAA 4194/4885HDAC3 1561/4885HDAC4 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.