Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028843 | 0.95 | TACR1 (0.55) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL13588071 | 0.91 | MDM4 (0.61) | MDM4MDM2OPRD1OPRM1CTSL | |
| SCHEMBL28902023 | 0.91 | MDM4 (0.61) | MDM4MDM2OPRD1OPRM1CTSL | |
| SCHEMBL19088181 | 0.89 | OPRD1 (0.50) | MDM4MDM2OPRD1OPRM1CTSL | |
| SCHEMBL23983030 | 0.89 | OPRD1 (0.52) | TACR1MDM4MDM2OPRD1OPRM1 | |
| SCHEMBL24312089 | 0.89 | OPRD1 (0.52) | TACR1MDM4MDM2OPRD1OPRM1 | |
| SCHEMBL13588070 | 0.89 | MME (0.56) | OPRD1OPRM1CTSLCTSBCTSS | |
| SCHEMBL19065177 | 0.89 | MME (0.56) | OPRD1OPRM1CTSLCTSBCTSS | |
| SCHEMBL11199738 | 0.88 | CTSL (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL28620426 | 0.87 | MDM4 (0.52) | MDM4MDM2OPRD1OPRM1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551272-A | Derivatives of dipeptide and their use in determining the activity of carboxypeptidase A | FUJIREBIO KABUSHIKI KAISHA (JP) | 1985-11-05 | — | — | US | disclosed |
| EP-0150227-A1 | Dipeptide derivatives and their use in determining the activity of carboxypeptidase A | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-08-07 | — | — | EP | disclosed |
| US-4173563-A | PEPTIDIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-11-06 | — | — | US | disclosed |
| US-4120853-A | Esterification of carboxylic acids by contact with a phosphonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-10-17 | — | — | US | disclosed |
| US-4059603-A | Esterification of carboxylic acids by contact with a phosphonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-11-22 | — | — | US | disclosed |
| US-3974219-A | PREPARATION PEPTIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |