(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL10948972

CCOCC.ClCc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 4/20 0.42
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TTR P02766 1/20 0.38
CALM1 P0DP23 1/20 0.38
IDO1 P14902 2/20 0.36
LTA4H P09960 2/20 0.35
CYP2D6 P10635 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL27554242 0.85 TP53 (0.55) TP53TSHRALDH1A1CALM1IDO1
(Chloromethyl)Benzene SCHEMBL27439570 0.84 IDO1 (0.50) TP53TSHRTTRIDO1CYP2D6
(Chloromethyl)Benzene SCHEMBL27327539 0.82 TP53 (0.46) TP53TSHRALDH1A1TTRCALM1
(Chloromethyl)Benzene SCHEMBL4637240 0.82 TP53 (0.50) TP53TSHRALDH1A1CALM1IDO1
(Chloromethyl)Benzene SCHEMBL6422666 0.82 CALM1 (0.53) TP53TSHRALDH1A1SMN1; SMN2CALM1
SCHEMBL21317609 0.82 CALM1 (0.53) TP53TSHRALDH1A1SMN1; SMN2CALM1
(Chloromethyl)Benzene SCHEMBL7413 0.82
(Chloromethyl)Benzene SCHEMBL1331085 0.82
(Chloromethyl)Benzene SCHEMBL29919724 0.82
(Chloromethyl)Benzene SCHEMBL1616642 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107098792-A A kind of tetrachloro-ethylene pays the production method that discarded object produces phenyl-hexafluoride 衢州乾达科技有限公司 2017-08-29 CN claimed
CN-107098792-A A kind of tetrachloro-ethylene pays the production method that discarded object produces phenyl-hexafluoride 衢州乾达科技有限公司 2017-08-29 CN disclosed
CN-103805208-A Dicyclohexyl ethylene group substituted diphenylacetylene liquid crystal compound and preparation method thereof UNIV SHAANXI NORMAL 2014-05-21 CN disclosed
CN-103073578-A Dibenzyl phosphinic acid synthetic method UNIV TSINGHUA 2013-05-01 CN disclosed
US-4545934-A ALKYLATION OF THE ESTER AND AMIDE DERIVATIVES LONZA LTD. (CH) 1985-10-08 US disclosed