(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL27554242

CCCl.ClCc1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.55
CALM1 P0DP23 1/20 0.45
TSHR P16473 5/20 0.42
ALDH1A1 P00352 4/20 0.42
IDO1 P14902 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TRPA1 O75762 1/20 0.41
CYP2D6 P10635 1/20 0.41
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL4637240 0.91 TP53 (0.50) TP53CALM1TSHRALDH1A1IDO1
(Chloromethyl)Benzene SCHEMBL1616642 0.91
(Chloromethyl)Benzene SCHEMBL29794364 0.91
(Chloromethyl)Benzene SCHEMBL4746769 0.91 CALM1 (0.53) TP53CALM1TSHRALDH1A1IDO1
(Chloromethyl)Benzene SCHEMBL1331085 0.91
(Chloromethyl)Benzene SCHEMBL6422666 0.91 CALM1 (0.53) TP53CALM1TSHRALDH1A1IDO1
(Chloromethyl)Benzene SCHEMBL29919724 0.91
(Chloromethyl)Benzene SCHEMBL7413 0.91
SCHEMBL21317609 0.91 CALM1 (0.53) TP53CALM1TSHRALDH1A1IDO1
(Chloromethyl)Benzene SCHEMBL5157581 0.89 LOXL2 (0.50) TP53CALM1LOXL2CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105264002-B Resin combination, optical compensation films and its manufacture method using it 东曹株式会社 2017-11-10 CN disclosed
CN-1284808-C Poly(p-phenyl acetylene derivative, its preparation and use FUDAN TIANCHEN NEW TECHNOLOGY (CN) 2006-11-15 CN disclosed
CN-1644596-A Poly(p-phenyl acetylene derivative, its preparation and use FUDAN TIANCHEN NEW TECHNOLOGY (CN) 2005-07-27 CN disclosed