Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247589 | 0.86 | KMT2A (0.49) | KMT2AFOLH1PTGER4PTGER3PTGER2 | |
| SCHEMBL10451654 | 0.85 | PTGER4 (0.56) | KMT2APTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL11063801 | 0.80 | GPR52 (0.48) | KMT2AFOLH1PTGER4PTGER3PTGER2 | |
| SCHEMBL8717020 | 0.79 | DPP4 (0.50) | KMT2AFOLH1PTGER4PTGER3PTGER2 | |
| SCHEMBL1006202 | 0.78 | AKR1B1 (0.53) | KMT2APTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL28743677 | 0.78 | AKR1B1 (0.53) | KMT2APTGER4PTGER3PTGER2MEN1 | |
| SCHEMBL8698401 | 0.76 | GPR52 (0.51) | KMT2APTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL8698403 | 0.76 | GPR52 (0.51) | KMT2APTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL6361489 | 0.76 | FOLH1 (0.50) | FOLH1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL27623546 | 0.76 | PTGER4 (0.49) | KMT2APTGER4PTGER3PTGER2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537906-A | Substituted phenylalkenoic acids and esters | MERCK FROSST CANADA, INC. (CA) | 1985-08-27 | — | — | US | disclosed |