Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445897 | 0.92 | CES1 (0.54) | ALDH1A1HPGDL3MBTL1TDP1MEN1 | |
| SCHEMBL4421929 | 0.92 | ALDH1A1 (0.48) | ALDH1A1SRD5A2ELANEHPGDLMNA | |
| SCHEMBL29242363 | 0.84 | SMN1; SMN2 (0.55) | ALDH1A1RAB9AHPGDNPC1L3MBTL1 | |
| SCHEMBL17479953 | 0.83 | ALDH1A1 (0.61) | ALDH1A1SRD5A2ELANERAB9AHPGD | |
| Benzophenone SCHEMBL6662205 | 0.82 | ALDH1A1 (0.82) | ALDH1A1SRD5A2ELANERAB9AHPGD | |
| SCHEMBL10941702 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SRD5A2ELANERAB9AHPGD | |
| Benzophenone SCHEMBL28165766 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SRD5A2ELANERAB9AHPGD | |
| SCHEMBL677086 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SRD5A2ELANERAB9AHPGD | |
| SCHEMBL10946280 | 0.79 | LMNA (0.59) | ALDH1A1SRD5A2ELANERAB9ANPC1 | |
| Benzophenone SCHEMBL22829712 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SRD5A2ELANERAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |