SCHEMBL10949577

SCHEMBL10949577

Clc1ccc(C=NCCN=Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.56
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
AMY1A P0DUB6 1/20 0.45
G6PC1 P35575 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10949573 1.00 MAOB (0.56) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19434695 0.91 MAOB (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19434666 0.91 MAOB (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11672656 0.91 MAOB (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21882610 0.89 RAB9A (0.50) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11353941 0.83 ALDH1A1 (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11353938 0.83 ALDH1A1 (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11260773 0.81 MAOB (0.52) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19233524 0.80 ALDH1A1 (0.49) MAOBKMT2AALDH1A1MEN1MAPK1
SCHEMBL3067898 0.80 TAAR1 (0.70) GRIN1GRIN2BALDH1A1G6PC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4507284-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-03-26 US disclosed
EP-0031054-B1 SOIL DISINFECTANT COMPOSITION, A METHOD FOR PREVENTING AND CONTROLLING DISEASES IN SOIL AND CERTAIN PHENYLPHOSPHINIC ACID SALTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-29 EP disclosed
US-4366150-A SATURATED HETEROCYCLIC AMINE SALT OF PHENYLPHOSPHINIC ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-12-28 US disclosed
EP-0031054-A1 Soil disinfectant composition, a method for preventing and controlling diseases in soil and certain phenylphosphinic acid salts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP disclosed