Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 6/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365547 | 0.81 | PDE4A (0.36) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10763411 | 0.79 | PDE3B (0.51) | ADH5PDE3BPDE3APDE2APDE1A | |
| SCHEMBL10363287 | 0.77 | PDE4A (0.42) | ADH5PDE3BPDE3APDE2APDE1A | |
| SCHEMBL10363632 | 0.75 | PDE3B (0.38) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10365504 | 0.75 | PDE4A (0.40) | ADH5PDE3BPDE3APDE2APDE1A | |
| SCHEMBL10762086 | 0.75 | PDE4B (0.52) | ADH5PDE3BPDE3APDE2APDE4A | |
| SCHEMBL10756489 | 0.75 | PDE3B (0.55) | ADH5PDE3BPDE3APDE2APDE1A | |
| SCHEMBL10763565 | 0.74 | PDE3B (0.53) | ADH5PDE3BPDE3APDE2APDE1A | |
| SCHEMBL10363624 | 0.71 | PDE4A (0.37) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL10363623 | 0.68 | PDE4A (0.44) | ADH5PDE3BPDE3APDE2APDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175187-A1 | 3,4-Dihydro-2(1H)-pyridones and 2(1H)-pyridones containing imidazole groups, method for their preparation and medicaments containing them | A. Nattermann & Cie. GmbH (DE) | 1986-03-26 | — | — | EP | disclosed |