SCHEMBL1095064

SCHEMBL1095064

COC([SiH3])(CNCCN)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.39
CA6 P23280 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA5B Q9Y2D0 3/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA2 P00918 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA5A P35218 2/20 0.38
CA1 P00915 1/20 0.38
ALOX15 P16050 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56116 0.80 TSHR (0.42) ALDH1A1
SCHEMBL56585 0.79
SCHEMBL40404 0.78 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL11036494 0.77 CA12 (0.42) CA12CA6CA7CA9CA14
SCHEMBL5682045 0.77 TSHR (0.46) LMNAALDH1A1
SCHEMBL6444276 0.75 CA12 (0.41) CA12CA6CA7CA9CA14
Ammonia Solution, Strong SCHEMBL22712951 0.75 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL57589 0.73 TP53 (0.35) TP53
SCHEMBL2464400 0.72 CA12 (0.31) CA12CA6CA7CA9CA14
SCHEMBL57611 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3401366-B1 SILICONE COMPOSITION BASED ON BOTH CONDENSATION CURING REACTION AND ORGANIC-PEROXIDE CURING REACTION SHINETSU CHEMICAL CO (JP) 2020-08-26 EP disclosed
US-10689515-B2 Silicone composition based on both condensation/curing reaction and organic-peroxide curing reaction SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-23 US disclosed
US-20190010294-A1 SILICONE COMPOSITION BASED ON BOTH CONDENSATION/CURING REACTION AND ORGANIC-PEROXIDE CURING REACTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-01-10 US disclosed
EP-3401366-A1 SILICONE COMPOSITION BASED ON BOTH CONDENSATION/CURING REACTION AND ORGANIC-PEROXIDE CURING REACTION Shin-Etsu Chemical Co., Ltd. (JP) 2018-11-14 EP disclosed
US-9238734-B2 Room temperature and humidity thickening thermo-conductive silicon grease composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-01-19 US disclosed
EP-2743315-A1 ROOM TEMPERATURE AND HUMIDITY THICKENING THERMO-CONDUCTIVE SILICON GREASE COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-18 EP disclosed
US-8658754-B2 Moisture-thickening heat-conductive silicone grease composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-02-25 US disclosed
EP-2439241-B1 Moisture-thickening heat-conductive silicone grease composition SHINETSU CHEMICAL CO (JP) 2013-04-03 EP disclosed
US-20120085964-A1 MOISTURE-THICKENING HEAT-CONDUCTIVE SILICONE GREASE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-12 US disclosed
US-8153747-B2 Two-part organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-10 US disclosed
US-20110034613-A1 TWO-PART ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-10 US disclosed
EP-1191066-B1 Room temperature-curing organopolysiloxane composition SHINETSU CHEMICAL CO (JP) 2005-11-09 EP disclosed
US-6573356-B2 Used for building construction or used in the bonding or fixing of electric or electronic component parts SHIN-ETSU CHEMICAL CO. LTD. (JP) 2003-06-03 US disclosed
US-20020065385-A1 Room temperature-curing organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-30 US disclosed
EP-1191066-A2 Room temperature-curing organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-27 EP disclosed