Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 8/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778591 | 0.98 | CYP2C19 (0.51) | CYP2C19TSHRCNR2SIGMAR1NR1H2 | |
| SCHEMBL10775309 | 0.95 | CYP2C19 (0.54) | CYP2C19TSHRCNR2SIGMAR1NR1H2 | |
| SCHEMBL9619470 | 0.89 | CYP2C19 (0.58) | CYP2C19TSHRCNR2NR1H2NR1H3 | |
| SCHEMBL51810 | 0.82 | CYP2C19 (0.61) | CYP2C19TSHRCNR2NR1H2NR1H3 | |
| SCHEMBL27702362 | 0.82 | SIGMAR1 (0.53) | CYP2C19CNR2SIGMAR1HTR2AHRH1 | |
| SCHEMBL10776429 | 0.80 | CNR2 (0.52) | TSHRCNR2SIGMAR1 | |
| SCHEMBL10776390 | 0.80 | CYP2C19 (0.47) | CYP2C19TSHRCNR2NR1H2NR1H3 | |
| SCHEMBL9750099 | 0.80 | CYP2C19 (0.47) | CYP2C19TSHRCNR2NR1H2NR1H3 | |
| SCHEMBL10779695 | 0.79 | CYP2C19 (0.46) | CYP2C19TSHRCNR2NR1H2NR1H3 | |
| SCHEMBL81907 | 0.77 | SIGMAR1 (0.64) | CYP2C19SIGMAR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539282-A | SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0115198-A1 | Electrophotographic photoconductive elements | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |