Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 13/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775309 | 0.84 | CYP2C19 (0.54) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL11106441 | 0.82 | CNR2 (0.46) | TSHRCNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL10781389 | 0.81 | MAPT (0.44) | TSHRCNR2ALDH1A1 | |
| SCHEMBL8086502 | 0.80 | ALDH1A1 (0.49) | CNR2KDM4EALDH1A1 | |
| SCHEMBL10951456 | 0.80 | CYP2C19 (0.53) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL9750090 | 0.79 | TSHR (0.39) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL10778591 | 0.78 | CYP2C19 (0.51) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL10778766 | 0.78 | CYP2C19 (0.54) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL9619470 | 0.77 | CYP2C19 (0.58) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL51810 | 0.77 | CYP2C19 (0.61) | CYP2C19TSHRNR1H2NR1H3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118986-A | Electroluminescent device | RICOH COMPANY, LTD. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0115198-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTIVE ELEMENTS | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4539282-A | SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0115198-A1 | Electrophotographic photoconductive elements | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |