Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | ICMT | O60725 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956818 | 1.00 | NPC1 (0.55) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL4744062 | 1.00 | NPC1 (0.55) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL10951817 | 1.00 | NPC1 (0.55) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL3982113 | 1.00 | NPC1 (0.55) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL6326806 | 0.98 | NPC1 (0.53) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL3342781 | 0.93 | CNR2 (0.48) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL430658 | 0.86 | TP53 (0.49) | NPC1RAB9APAX8JAK2CNR2 | |
| SCHEMBL7643003 | 0.85 | PLA2G2A (0.46) | NPC1RAB9APAX8JAK2PLA2G2A | |
| SCHEMBL9122844 | 0.85 | GPR84 (0.55) | NPC1RAB9APAX8JAK2ICMT | |
| SCHEMBL9124134 | 0.85 | NPC1 (0.54) | NPC1RAB9APAX8JAK2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492683-A | Method for inhibiting the growth of fungi with phenyl glycine compounds | BUFFALO COLOR CORPORATION (US) | 1985-01-08 | — | — | US | claimed |
| US-4492683-A | Method for inhibiting the growth of fungi with phenyl glycine compounds | BUFFALO COLOR CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |