Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326806 | 0.87 | NPC1 (0.53) | PLA2G2ABLMCNR2KDM4EALDH1A1 | |
| SCHEMBL8905205 | 0.86 | CYP3A4 (0.46) | PLA2G2ABLMCNR2ALDH1A1GAA | |
| SCHEMBL15518329 | 0.86 | CNR2 (0.48) | PLA2G2ABLMCNR2 | |
| SCHEMBL3982113 | 0.85 | NPC1 (0.55) | PLA2G2ABLMCNR2ALDH1A1NPC1 | |
| SCHEMBL10956818 | 0.85 | NPC1 (0.55) | PLA2G2ABLMCNR2ALDH1A1NPC1 | |
| SCHEMBL10951817 | 0.85 | NPC1 (0.55) | PLA2G2ABLMCNR2ALDH1A1NPC1 | |
| SCHEMBL4744062 | 0.85 | NPC1 (0.55) | PLA2G2ABLMCNR2ALDH1A1NPC1 | |
| SCHEMBL10952007 | 0.85 | NPC1 (0.55) | PLA2G2ABLMCNR2ALDH1A1NPC1 | |
| SCHEMBL1834462 | 0.84 | NR1H2 (0.50) | HSD17B3NR1H2NR1H3CNR2ESR1 | |
| SCHEMBL11667468 | 0.83 | CNR2 (0.50) | PLA2G2ABLMCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437175-B2 | MILD REACTION CONDITIONS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2002-08-20 | — | — | US | claimed |
| JP-52130987-A | — | — | None | — | — | JP | disclosed |
| CN-107987023-A | A kind of method of solid acid catalysis synthesis 4-Hydroxyphenyl hydantoin | 天津市职业大学 | 2018-05-04 | — | — | CN | disclosed |
| US-6437175-B2 | MILD REACTION CONDITIONS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20010031890-A1 | Process for the racemization of nu-acylamino acids by means of transition metal catalysts | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2001-10-18 | — | — | US | disclosed |
| EP-1136466-A2 | Process for racemising N-acyl-amino acids with transition metal catalysts | Aventis Research & Technologies GmbH & Co KG (DE) | 2001-09-26 | — | — | EP | disclosed |
| US-4309362-A | SEEDING SUPERSATURATED SOLUTION WITH CRYSTAL OF ENANTIOMORPH | TANABE SEIYAKU CO., LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| JP-S52130987-A | OPTICAL RESOLUTION OF N-ACYL-P-HYDROXY-DL-PHENYLGLYCINE | NIPPON SODA CO LTD | 1977-11-02 | — | — | JP | disclosed |