Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.65 |
| ▸ | FNTB | P49356 | 5/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953466 | 1.00 | FNTA (0.65) | FNTAFNTBSLC6A3MEN1KMT2A | |
| SCHEMBL10948798 | 0.92 | SMN1; SMN2 (0.65) | FNTAFNTBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10954657 | 0.86 | SMN1; SMN2 (0.66) | FNTAFNTBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10952833 | 0.86 | HTT (0.58) | FNTAFNTBMEN1KMT2APOLB | |
| SCHEMBL10946871 | 0.85 | KMT2A (0.60) | FNTAFNTBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10952227 | 0.85 | LMNA (0.72) | FNTAFNTBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10954976 | 0.85 | LMNA (0.68) | FNTAFNTBSLC6A3MEN1KMT2A | |
| SCHEMBL10950719 | 0.85 | CA12 (0.58) | FNTAFNTBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10945669 | 0.85 | FNTA (0.54) | FNTAFNTBMEN1KMT2APOLB | |
| SCHEMBL10953096 | 0.84 | LMNA (0.76) | FNTAFNTBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | claimed |