Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948798 | 0.92 | SMN1; SMN2 (0.65) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10954657 | 0.86 | SMN1; SMN2 (0.66) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10954976 | 0.85 | LMNA (0.68) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10952111 | 0.85 | FNTA (0.65) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10953466 | 0.85 | FNTA (0.65) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10950719 | 0.85 | CA12 (0.58) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10951751 | 0.84 | LMNA (1.00) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10949698 | 0.84 | TACR1 (0.59) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10953663 | 0.84 | CA12 (0.57) | LMNAGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL10948604 | 0.82 | LMNA (0.78) | LMNAGAAKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | claimed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | claimed |