Ethane

Ethane

SCHEMBL10952941

CC.CC(=O)OC(=O)Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ALDH1A1 P00352 4/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MAPK1 P28482 1/20 0.55
PAM P19021 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
AKR1B1 P15121 1/20 0.50
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
MEN1 O00255 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248114 0.98 TSHR (0.58) TSHRALDH1A1L3MBTL1MAPK1PAM
Acetic Acid SCHEMBL28845782 0.96 TSHR (0.56) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL28239334 0.85 PAM (0.66) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL248113 0.85 ALDH1A1 (0.65) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL9676563 0.84 TSHR (0.49) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL27643464 0.84 TSHR (0.53) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL6628783 0.82 TSHR (0.55) TSHRALDH1A1L3MBTL1MAPK1PAM
Phenylacetic Acid SCHEMBL28239335 0.82 AKR1B1 (0.71) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL27139938 0.82 TSHR (0.58) TSHRALDH1A1L3MBTL1MAPK1PAM
SCHEMBL27738415 0.81 MAPK1 (0.61) TSHRALDH1A1L3MBTL1MAPK1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4531008-A Insecticide, miticide SUMITOMO CHEMICAL CO., LTD. (JP) 1985-07-23 US disclosed
US-4266074-A SUBSTITUTED PHENYL BUTENYL ACETATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1981-05-05 US disclosed
EP-0006284-B1 RACEMIZING OF OPTICALLY ACTIVE ALPHA-SUBSTITUTED-ALPHA-PHENYLACETIC ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-04-08 EP disclosed
US-4245116-A REACTING WITH AN ALKALI METAL OR ALKALINE EARTH METAL HYDROXIDE OR CARBONATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-13 US disclosed
US-4237313-A HEATING TO 150C SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-12-02 US disclosed
EP-0006284-A1 Racemizing of optically active alpha-substituted-alpha-phenylacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-01-09 EP disclosed
US-4062968-A MITICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-12-13 US disclosed
US-4058622-A Substituted phenyl acetate, insecticidal composition and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-11-15 US disclosed
US-4039680-A SULFUR CONTAINING HETEROCYCLES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US disclosed
US-4031235-A Insecticidal substituted acetate compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-21 US disclosed
US-3996244-A Insecticidal esters of substituted furan methanol SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-12-07 US disclosed