SCHEMBL10952991

SCHEMBL10952991

C/C(=N/O)C(=O)Sc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MTNR1A P48039 4/20 0.37
MTNR1B P49286 4/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
FFAR1 O14842 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP2C19 P33261 2/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
GFER P55789 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270690 0.79 HPGD (0.47) HPGDALDH1A1MTNR1AMTNR1BFFAR1
SCHEMBL3087191 0.78 FFAR1 (0.48) HPGDALDH1A1FFAR1NPSR1CYP2C19
SCHEMBL544810 0.75 HPGD (0.44) HPGDALDH1A1MTNR1AMTNR1BFFAR1
SCHEMBL12897524 0.74 HPGD (0.38) HPGDALDH1A1MTNR1AMTNR1BMEN1
SCHEMBL8722202 0.74 HPGD (0.38) HPGDALDH1A1MTNR1AMTNR1BMEN1
SCHEMBL8722205 0.74 HPGD (0.38) HPGDALDH1A1MTNR1AMTNR1BMEN1
SCHEMBL17322710 0.73 FFAR1 (0.44) HPGDALDH1A1FFAR1NPSR1CYP1A2
SCHEMBL342299 0.73 CA12 (0.54) HPGDALDH1A1MTNR1AMTNR1BFFAR1
SCHEMBL17335274 0.71 TSHR (0.45) HPGDALDH1A1MTNR1AMTNR1BMEN1
SCHEMBL20827294 0.70 FFAR1 (0.41) HPGDALDH1A1FFAR1NPSR1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4509970-A Substituted phenylphosphinyloxy- and phosphinylthio-iminocarboxylates useful for the control of weeds ZOECON CORPORATION (US) 1985-04-09 US disclosed