Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12897524 | 1.00 | HPGD (0.38) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL8722205 | 1.00 | HPGD (0.38) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL15396167 | 0.79 | MAPT (0.39) | HPGDMAPTALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12923826 | 0.75 | MAPT (0.41) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL10952991 | 0.74 | HPGD (0.41) | HPGDMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1454790 | 0.74 | HPGD (0.45) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL2374205 | 0.70 | MAPT (0.41) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL10774029 | 0.70 | HPGD (0.41) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL342299 | 0.70 | CA12 (0.54) | HPGDMAPTALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL7049341 | 0.70 | MAPT (0.41) | HPGDMAPTALDH1A1SMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858511-A1 | PLANTS WITH REDUCED CLUCOSINOLATE CONTENT | PLANT GENETIC SYSTEMS N.V. (BE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997016559-A1 | PLANTS WITH REDUCED GLUCOSINOLATE CONTENT | PLANT GENETIC SYSTEMS, N.V. (BE) | 1997-05-09 | — | — | WO | disclosed |
| EP-0771878-A1 | Plants with reduced glucosinolate content | PLANT GENETIC SYSTEMS N.V. (BE) | 1997-05-07 | — | — | EP | disclosed |