SCHEMBL544810

SCHEMBL544810

C=C(C)C(=O)Sc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.41
MTNR1A P48039 4/20 0.39
MTNR1B P49286 4/20 0.39
FFAR1 O14842 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ELANE P08246 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ALPG P10696 1/20 0.36
HSD17B10 Q99714 2/20 0.35
NAPRT Q6XQN6 1/20 0.35
MAPT P10636 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1803064 0.89 HPGD (0.39) HPGDALDH1A1KDM4EMAPTLMNA
SCHEMBL1412683 0.88 SMN1; SMN2 (0.47) HPGDALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL1803065 0.85 TDP1 (0.37) HPGDALDH1A1KDM4EMTNR1AMTNR1B
SCHEMBL158581 0.83 HPGD (0.50) HPGDALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL16170747 0.83 L3MBTL1 (0.35) HPGDALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL7575059 0.83 L3MBTL1 (0.35) HPGDALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL16170509 0.83 L3MBTL1 (0.35) HPGDALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL7270690 0.82 HPGD (0.47) HPGDALDH1A1MTNR1AMTNR1BFFAR1
Methacrylic Acid SCHEMBL9350828 0.82 HPGD (0.45) HPGDALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL9446514 0.81 SIRT1 (0.46) HPGDALDH1A1KDM4ECA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080146729-A1 Aqueous ink composition and method of manufacturing the same SEIKO EPSON CORPORATION 2008-06-19 US claimed
US-7374799-B2 Radiation sensitive composition, microlens, process for forming microlens and use of the microlens JSR CORPORATION (JP) 2008-05-20 US claimed
US-20050004261-A1 Aqueous ink composition and method of manufacturing the same SEIKO EPSON CORPORATION 2005-01-06 US claimed
EP-4378928-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-06-05 EP disclosed
US-20230399563-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC ARTICLE AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-12-14 US disclosed
US-20230359068-A1 OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND HOYA LENS THAILAND LTD. (TH) 2023-11-09 US disclosed
EP-4206799-A1 OPTICAL ARTICLE, EYEGLASSES AND PHOTOCHROMIC COMPOUND Hoya Lens Thailand Ltd. (TH) 2023-07-05 EP disclosed
EP-4067353-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC ARTICLE AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2022-10-05 EP disclosed
US-9205144-B2 Identification of conserved peptide blocks in homologous polypeptides DANA-FARBER CANCER INSTITUTE, INC. (US) 2015-12-08 US disclosed
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
US-5214116-A Acrylic polymers with thioester group, lenses, optical fibers, optical recording media TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1993-05-25 US disclosed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US disclosed
US-4791183-A 1,2-DIHALOETHYL STYRENES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-12-13 US disclosed
US-4732887-A RESIN IN VOIDS FOR CHROMATOGRAPHY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-03-22 US disclosed
EP-0060472-B1 A METHOD FOR SEPARATING T CELLS FROM LEUKOCYTES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-12-17 EP disclosed
US-4430445-A POLYAMIDINE HOHO- AND COPOLYMERS; OXIDATION RESISTANCE; METAL EXTRACTION; POLYEPOXIDE CURING AGENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-02-07 US disclosed
US-4425237-A Method for separating T cells from leukocytes ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-01-10 US disclosed
EP-0060472-A2 A method for separating T cells from leukocytes Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-09-22 EP disclosed
US-4202775-A CROSSLINKABLE ETHYLENICALLY UNSATURATED POROUS COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD PUF60, PARG, FHIT HPGD 2353/4885ALDH1A1 3106/4885KDM4E 1254/4885
US-20230359068-A1 OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND GRK1, TCOF1, ARPC1B HPGD 3825/4885ALDH1A1 1971/4885KDM4E 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.