Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114844 | 1.00 | ALDH1A1 (0.39) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL11118067 | 0.88 | PTGDR2 (0.41) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL10951862 | 0.88 | PTGDR2 (0.41) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL11120298 | 0.85 | ALDH1A1 (0.34) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL11120300 | 0.85 | ALDH1A1 (0.34) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL10865234 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL10949315 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SLCO2A1PTGER4PTGER1PTGER3 | |
| SCHEMBL11128286 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL11119080 | 0.84 | PTGER4 (0.33) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 | |
| SCHEMBL11119201 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SLCO2A1PTGDR2PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562204-A | ANTITUMOR, ANTILEUKEMIA AGENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0099672-A2 | Trans-Delta 2-prostaglandin D derivatives, process for their preparation and compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |