Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | PTGFR | P43088 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951862 | 1.00 | PTGDR2 (0.41) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL10952197 | 0.91 | PTGDR2 (0.36) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER2 | |
| SCHEMBL10865234 | 0.89 | ALDH1A1 (0.55) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL11114844 | 0.88 | ALDH1A1 (0.39) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL10953111 | 0.88 | ALDH1A1 (0.39) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL11128286 | 0.88 | ALDH1A1 (0.47) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL11119201 | 0.86 | ALDH1A1 (0.46) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D | |
| SCHEMBL10952666 | 0.85 | ITGB1 (0.31) | PTGDR2ALDH1A1SLCO2A1 | |
| SCHEMBL10954137 | 0.84 | PDE4D (0.43) | ALDH1A1SLCO2A1PDE4DPTGER4TBXA2R | |
| SCHEMBL11117356 | 0.84 | PTGDR2 (0.44) | PTGDR2ALDH1A1SLCO2A1GALR3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099672-A2 | Trans-Delta 2-prostaglandin D derivatives, process for their preparation and compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |