Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953133 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TDP1ALOX15 | |
| SCHEMBL11037655 | 0.87 | SOAT2 (0.35) | ALDH1A1LMNAHSD17B10TDP1ALOX15 | |
| SCHEMBL11037656 | 0.87 | SOAT2 (0.35) | ALDH1A1LMNAHSD17B10TDP1ALOX15 | |
| SCHEMBL10953596 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHRPTPN1PRKCA | |
| SCHEMBL10953598 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHRPTPN1PRKCA | |
| SCHEMBL7667132 | 0.84 | TSHR (0.36) | ALDH1A1LMNAHSD17B10TDP1TSHR | |
| SCHEMBL7667124 | 0.84 | TSHR (0.36) | ALDH1A1LMNAHSD17B10TDP1TSHR | |
| SCHEMBL11411944 | 0.82 | GALR3 (0.40) | ALDH1A1PRKCA | |
| SCHEMBL11411941 | 0.82 | GALR3 (0.40) | ALDH1A1PRKCA | |
| SCHEMBL11025670 | 0.81 | TDP1 (0.32) | ALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544767-A | HYDROGENATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | claimed |
| US-4544767-A | HYDROGENATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | disclosed |