Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398827 | 0.77 | KDM4E (0.54) | HTTCYP3A4HPGDSMN1; SMN2KMT2A | |
| SCHEMBL10821087 | 0.77 | KDM4E (0.54) | HTTCYP3A4HPGDSMN1; SMN2KMT2A | |
| SCHEMBL8350121 | 0.75 | HTT (0.53) | HTTCYP3A4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL1258995 | 0.75 | HTT (0.60) | HTTCYP3A4TSHRRECQLHPGD | |
| SCHEMBL10507031 | 0.74 | HTT (0.43) | HTTCYP3A4HPGDSMN1; SMN2KMT2A | |
| SCHEMBL29583577 | 0.74 | MKNK1 (0.47) | HTTCYP3A4TSHRRECQLHPGD | |
| SCHEMBL8292066 | 0.73 | ALDH1A1 (0.63) | TSHRHPGDSMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL9750778 | 0.73 | CYP3A4 (0.50) | HTTCYP3A4TSHRRECQLHPGD | |
| SCHEMBL8472608 | 0.72 | HTT (0.62) | HTTCYP3A4TSHRRECQLHPGD | |
| SCHEMBL18988716 | 0.71 | STAT3 (0.53) | HTTCYP3A4RECQLHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102516252-A | Preparation method of Nedocromil sodium | SICHUAN DIHON MEDICAL DEV CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-102516252-A | Preparation method of Nedocromil sodium | SICHUAN DIHON MEDICAL DEV CO LTD | 2012-06-27 | — | — | CN | disclosed |
| EP-0030423-B1 | A PROCESS FOR THE PRODUCTION OF 1,4-DIHYDRO-4-OXO-QUINOLINE-2-CARBOXYLIC ACIDS, OR SALTS, ESTERS OR AMIDES THEREOF AND INTERMEDIATES THEREFOR | FISONS plc (GB) | 1985-02-13 | — | — | EP | disclosed |
| US-4414416-A | Certain diacetyl-amino-phenolic derivatives | FISONS LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| US-4328341-A | Process for preparing certain pyrano[3,2-g]quinoline 2,8-dicarboxylates and 4-oxo-quinoline-2-carboxylates | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |
| EP-0030423-A1 | A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor | FISONS plc (GB) | 1981-06-17 | — | — | EP | disclosed |