Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL10954936

CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C([O-])C(F)(F)F

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.43
TSHR P16473 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 2/20 0.43
CPA1 P15085 1/20 0.39
CES1 P23141 4/20 0.39
HIF1A Q16665 1/20 0.39
CES2 O00748 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 4/20 0.35
ALPL P05186 1/20 0.35
ALPG P10696 1/20 0.35
CYP2C9 P11712 2/20 0.35
ADORA1 P30542 1/20 0.35
MAPK1 P28482 1/20 0.35
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL1144353 0.87 CYP1A2 (0.50) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Bicarbonate SCHEMBL11663344 0.87 CYP1A2 (0.50) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL328882 0.85 TSHR (0.48) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL133341 0.85 TSHR (0.48) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Oxalic Acid SCHEMBL10577823 0.85 CYP1A2 (0.48) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL9467718 0.83 TSHR (0.47) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Propionic Acid SCHEMBL1399930 0.83 CYP1A2 (0.47) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL10484555 0.83 CYP1A2 (0.47) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL328881 0.83 TSHR (0.47) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2
Acetic Acid SCHEMBL27993794 0.83 TSHR (0.47) CYP2D6TSHRCYP2C19ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4496709-A REACTING AN EPOXIDE WITH A DIHYDRIC PHENOL OR A THIOPHENOLIC COMPOUND THE DOW CHEMICAL COMPANY (US) 1985-01-29 US claimed