Acetic Acid

Acetic Acid

SCHEMBL133341

CC(=O)[O-].CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
CYP1A2 P05177 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.44
CES2 O00748 4/20 0.41
CES1 P23141 4/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
POLB P06746 2/20 0.39
ALPL P05186 1/20 0.39
ALPG P10696 1/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL328882 1.00 TSHR (0.48) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL27993794 0.98 TSHR (0.47) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL10484555 0.98 CYP1A2 (0.47) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL9467718 0.98 TSHR (0.47) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL328881 0.98 TSHR (0.47) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL10422777 0.96 TSHR (0.46) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL1651995 0.96 TSHR (0.46) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Acetic Acid SCHEMBL10580400 0.96 TSHR (0.46) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Bicarbonate SCHEMBL1144353 0.94 CYP1A2 (0.50) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19
Bicarbonate SCHEMBL11663344 0.94 CYP1A2 (0.50) TSHRCYP1A2ALDH1A1CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1669 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562108-A1 EPOXY BASED PHASE CHANGE MATERIAL, COMPOSITION AND METHOD THEREOF Elantas Beck India Ltd. (IN) 2025-06-04 EP claimed
CN-119654390-A Epoxy-type phase change material, and composition and method thereof 艾伦塔斯贝克印度有限公司 2025-03-18 CN claimed
US-20250066968-A1 METHOD FOR DEGUMMING AND DECOLORIZING POLYESTER FABRIC NAN YA PLASTICS CORPORATION (TW) 2025-02-27 US claimed
CN-119507194-A Method for removing glue and decoloring polyester fabric 南亚塑胶工业股份有限公司 2025-02-25 CN claimed
CN-119019647-A Content-controllable high-activity hydroxyl modified solid epoxy resin and preparation method thereof 中国石油化工股份有限公司 2024-11-26 CN claimed
EP-4168510-B1 PHOSPHORUS-CONTAINING FLAME RETARDANT MIXTURES, A PROCESS FOR PRODUCTION OF SAID MIXTURES AND USE OF SAID MIXTURES, AND ALSO EPOXY RESIN FORMULATIONS WHICH COMPRISE SAID FLAME RETARDANT MIXTURES CLARIANT INT LTD (CH) 2024-07-10 EP claimed
WO-2024023846-A1 EPOXY BASED PHASE CHANGE MATERIAL, COMPOSITION AND METHOD THEREOF ELANTAS BECK INDIA LIMITED (IN) 2024-02-01 WO claimed
US-20230407154-A1 BLOCKED POLYURETHANE TOUGHENERS FOR EPOXY ADHESIVES DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) 2023-12-21 US claimed
US-20230272283-A1 PHOSPHORUS-CONTAINING FLAME RETARDANT MIXTURES, A PROCESS FOR PRODUCTION OF SAID MIXTURES AND USE OF SAID MIXTURES, AND ALSO EPOXY RESIN FORMULATIONS WHICH COMPRISE SAID FLAME RETARDANT MIXTURES CLARIANT INTERNATIONAL LTD (CH) 2023-08-31 US claimed
EP-4168510-A1 PHOSPHORUS-CONTAINING FLAME RETARDANT MIXTURES, A PROCESS FOR PRODUCTION OF SAID MIXTURES AND USE OF SAID MIXTURES, AND ALSO EPOXY RESIN FORMULATIONS WHICH COMPRISE SAID FLAME RETARDANT MIXTURES Clariant International Ltd (CH) 2023-04-26 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
US-4857566-A Curable latex composition, films and foams formed therefrom and method for curing the composition THE DOW CHEMICAL COMPANY (US) 1989-08-15 US claimed
US-4749728-A HAVING HYDROXY-FUNCTIONAL AND CARBOXYLIC ESTER-FUNCTIONAL RESINS OR COMPONENTS THE GLIDDEN COMPANY (US) 1988-06-07 US claimed
US-4742096-A EPOXIDE AND PHOSPHONIUM OR AMMONIUM SALT THE GLIDDEN COMPANY (US) 1988-05-03 US claimed
EP-0252289-A2 Transesterification catalysts and thermoset coatings THE GLIDDEN COMPANY (US) 1988-01-13 EP claimed
US-4358577-A Method for preparing high molecular weight epoxy resins containing hydrolyzed epoxy groups THE DOW CHEMICAL COMPANY (US) 1982-11-09 US claimed
US-4321304-A Beta-diketone-epoxy resin reaction products blended with monomeric or polymeric phosphonium salts useful for providing corrosion resistance PPG INDUSTRIES, INC. (US) 1982-03-23 US claimed
US-4321305-A Beta-diketone-epoxy resin reaction products useful for providing corrosion resistance PPG INDUSTRIES, INC. (US) 1982-03-23 US claimed
US-4053329-A METHOD OF IMPROVING CORROSION RESISTANCE OF METAL SUBSTRATES BY PASSIVATING WITH AN ONIUM SALT-CONTAINING MATERIAL PPG INDUSTRIES, INC. (US) 1977-10-11 US claimed
US-3948855-A Process for reacting a phenol with a vicinal epoxy compound in the presence of phosphorus or carbon containing acid, ester or acid ester THE DOW CHEMICAL COMPANY (US) 1976-04-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272283-A1 PHOSPHORUS-CONTAINING FLAME RETARDANT MIXTURES, A PROCESS FOR PRODUCTION OF SAID MIXTURES AND USE OF SAID MIXTURES, AND ALSO EPOXY RESIN FORMULATIONS WHICH COMPRISE SAID FLAME RETARDANT MIXTURES FFAR3, AFF1, RER1 TSHR 367/4885CYP1A2 455/4885ALDH1A1 850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.