Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550616 | 0.87 | PRMT1 (0.69) | PRMT1USP2CASP1CASP7HSD17B10 | |
| SCHEMBL11344636 | 0.83 | ALDH1A1 (0.50) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL11359996 | 0.79 | ALDH1A1 (0.46) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL25837913 | 0.78 | KDR (0.55) | USP2CASP1CASP7HSD17B10ALOX15 | |
| Propylamine SCHEMBL11711447 | 0.78 | PRMT1 (0.57) | PRMT1USP2CASP1CASP7HSD17B10 | |
| SCHEMBL27454006 | 0.76 | CDK5 (0.51) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL29532065 | 0.75 | KDR (0.48) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL8796831 | 0.75 | KDM4E (0.51) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL8482582 | 0.75 | KDR (0.48) | USP2CASP1CASP7HSD17B10ALOX15 | |
| SCHEMBL11689659 | 0.75 | USP2 (0.74) | USP2CASP1CASP7HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529804-A | Naphthostyril Ni or Cu complexes, a process for their preparation, and high molecular weight organic material pigmented with these metal complexes | CIBA-GEIGY CORPORATION (US) | 1985-07-16 | — | — | US | disclosed |
| US-4268668-A | FOR WOOL AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4246422-A | Naphtholactam dyestuffs | CIBA-GEIGY AG (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | disclosed |