Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956577 | 0.89 | NPC1 (0.41) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10956496 | 0.88 | NPC1 (0.52) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10953618 | 0.88 | NPC1 (0.44) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10957138 | 0.86 | BRD4 (0.44) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10951768 | 0.85 | MEN1 (0.44) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10957026 | 0.84 | ALDH1A1 (0.41) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11045131 | 0.83 | NPC1 (0.43) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10957311 | 0.80 | EDNRA (0.44) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10850605 | 0.79 | MAPT (0.42) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10650821 | 0.79 | GAA (0.49) | MAPTNPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046677-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-24 | — | — | EP | claimed |
| US-4487626-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-11 | — | — | US | claimed |
| EP-0046677-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4487626-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| EP-0046677-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-03 | — | — | EP | disclosed |