Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956496 | 0.90 | NPC1 (0.52) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10957026 | 0.83 | ALDH1A1 (0.41) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10955488 | 0.83 | MAPT (0.43) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL11038838 | 0.81 | KDM4E (0.47) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10953618 | 0.81 | NPC1 (0.44) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL11045452 | 0.81 | MAPT (0.40) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10956577 | 0.80 | NPC1 (0.41) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL11043929 | 0.80 | KDM4E (0.48) | NPC1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10957138 | 0.80 | BRD4 (0.44) | NPC1ALDH1A1KDM4ECA1CA9 | |
| SCHEMBL10951768 | 0.79 | MEN1 (0.44) | NPC1CA1MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | claimed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | claimed |
| US-4460404-A | HERBICIDES PLANT GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |