Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812190 | 0.85 | LMNA (0.68) | SMN1; SMN2NPC1LMNAHTTMAPT | |
| SCHEMBL10958946 | 0.85 | GAA (0.52) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL10956366 | 0.81 | NPC1 (0.62) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL16323195 | 0.78 | NPC1 (0.80) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL6091917 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL256855 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL17852523 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL19602918 | 0.75 | MAPT (0.75) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL11321060 | 0.74 | HMGCR (0.49) | SMN1; SMN2HTTMAPTKDM4EGAA | |
| SCHEMBL13284211 | 0.74 | HMGCR (0.68) | SMN1; SMN2NPC1RAB9AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500542-A | ADMINISTERING RIBOFLAVIN OR ANALOG ALONG WITH ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |