Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.54 |
| ▸ | WNT3A | P56704 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821807 | 0.87 | LMNA (0.79) | NPC1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30040198 | 0.87 | LMNA (0.79) | NPC1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3943149 | 0.86 | LMNA (0.83) | NPC1LMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL3730274 | 0.85 | ACHE (0.70) | NPC1LMNAHTTALDH1A1KDM4E | |
| SCHEMBL1515747 | 0.84 | NPC1 (0.63) | NPC1LMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL15988792 | 0.84 | CTNNB1 (0.74) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL6280969 | 0.82 | PDE4D (0.60) | NPC1LMNAHTTRAB9AALDH1A1 | |
| SCHEMBL10955656 | 0.81 | SMN1; SMN2 (0.64) | NPC1LMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL3940426 | 0.80 | HTT (0.61) | NPC1LMNAHTTRAB9AALDH1A1 | |
| SCHEMBL30969381 | 0.80 | LMNA (0.64) | NPC1LMNAHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500542-A | ADMINISTERING RIBOFLAVIN OR ANALOG ALONG WITH ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |