Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | DRD4 | P21917 | 7/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maroxepin SCHEMBL2108201 | 0.86 | SETD7 (0.69) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11573091 | 0.83 | SETD7 (0.76) | SETD7AHRCHRM2HTR1AADRA2A | |
| SCHEMBL10733741 | 0.83 | DRD4 (0.57) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10956945 | 0.80 | SETD7 (0.50) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11089507 | 0.79 | SETD7 (0.49) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL490256 | 0.78 | SETD7 (0.76) | SETD7AHRCHRM2HTR1AADRA2A | |
| SCHEMBL11083894 | 0.78 | SETD7 (0.48) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10956558 | 0.77 | CCR1 (0.47) | AHRDRD2MAPTHTR2AHTR2C | |
| SCHEMBL11089511 | 0.76 | SETD7 (0.46) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10729802 | 0.74 | CHRM2 (0.54) | SETD7CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492691-A | TRANSQUILIZERS, SEDATIVES | CIBA-GEIGY CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |
| EP-0030916-A1 | Azatetracyclic carbonitriles | CIBA-GEIGY AG (CH) | 1981-06-24 | — | — | EP | disclosed |