Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | DRD1 | P21728 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maroxepin SCHEMBL2108201 | 0.86 | SETD7 (0.69) | DRD4DRD2CYP1A2CYP2D6TP53 | |
| Clopipazan SCHEMBL1816896 | 0.83 | SETD7 (0.76) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10956547 | 0.83 | SETD7 (0.54) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13752344 | 0.80 | DRD4 (0.48) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10956945 | 0.80 | SETD7 (0.50) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11089507 | 0.79 | SETD7 (0.49) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11098584 | 0.78 | DRD2 (0.51) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11083894 | 0.78 | SETD7 (0.48) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| Clopipazan SCHEMBL120732 | 0.76 | SETD7 (0.64) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11648575 | 0.76 | MAPK1 (0.43) | DRD4DRD2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707476-A | TRANQUILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |