Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.59 |
| ▸ | PLAU | P00749 | 4/20 | 0.59 |
| ▸ | PLAT | P00750 | 4/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.59 |
| ▸ | KLK1 | P06870 | 3/20 | 0.59 |
| ▸ | KLK8 | O60259 | 2/20 | 0.59 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | KLK2 | P20151 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954084 | 0.83 | ELANE (0.55) | ELANECTSLACE2PRTN3MMP1 | |
| SCHEMBL10957871 | 0.81 | F2 (0.57) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL10957296 | 0.79 | F2 (0.59) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL10955973 | 0.79 | KYNU (0.56) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL10955767 | 0.76 | KLK1 (0.51) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL10955479 | 0.76 | F2 (0.55) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL10959861 | 0.74 | F2 (0.51) | F2PLAUPLATPLGKLK1 | |
| SCHEMBL18857044 | 0.73 | SMN1; SMN2 (0.62) | CTSL | |
| SCHEMBL15397862 | 0.73 | ACE2 (0.71) | ELANECTSLACE2PRTN3 | |
| SCHEMBL23881709 | 0.73 | ECE1 (0.50) | F2PLAUPLATPLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063896-B1 | AMINO AND SUBSTITUTED AMINO PHOSPHINYL-ALKANOYL COMPOSITIONS | E.R. Squibb & Sons, Inc. (US) | 1985-08-14 | — | — | EP | disclosed |