Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577480 | 0.87 | IDO1 (0.40) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10955853 | 0.82 | ALDH1A1 (0.43) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29870318 | 0.81 | IDO1 (0.54) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1537861 | 0.81 | IDO1 (0.54) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11108936 | 0.81 | ALDH1A1 (0.40) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10991114 | 0.80 | HPGD (0.51) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7954309 | 0.80 | IDO1 (0.53) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7954313 | 0.80 | IDO1 (0.53) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| Bromide SCHEMBL7951258 | 0.80 | IDO1 (0.53) | IDO1TDO2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8172135 | 0.79 | ALDH1A1 (0.43) | IDO1TDO2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053851-B1 | NOVEL ANTIFOGGING COMPOUNDS AND THEIR USE IN SILVER HALIDE PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1985-05-29 | — | — | EP | disclosed |
| US-4451555-A | 1-PHENYL-5-MERCAPTOTETRAZOLES | AGFA-GEVAERT, N.V. (BE) | 1984-05-29 | — | — | US | disclosed |
| EP-0053851-A1 | Novel antifogging compounds and their use in silver halide photography | AGFA-GEVAERT N.V. (BE) | 1982-06-16 | — | — | EP | disclosed |