Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955154 | 0.84 | MAPT (0.56) | PDE10AMAPTKDM4ENPC1RAB9A | |
| SCHEMBL10955026 | 0.82 | KDM4E (0.62) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10956622 | 0.81 | IDO1 (0.47) | PDE10AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL1173733 | 0.80 | MAPT (0.58) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6453590 | 0.78 | MAPT (0.43) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL704825 | 0.78 | PDE10A (0.59) | PDE10AMAPTKDM4ENPC1RAB9A | |
| SCHEMBL10959632 | 0.77 | NPC1 (0.50) | PDE10AMAPTKDM4ENPC1RAB9A | |
| SCHEMBL27936878 | 0.77 | MAPT (0.69) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23951 | 0.75 | MAPT (0.59) | PDE10AMAPTKDM4ENPC1RAB9A | |
| SCHEMBL10810821 | 0.74 | PDE10A (1.00) | PDE10AMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524123-A | POLYETHERSILOXANE COPOLYMERS, HIGH MOLECULAR WEIGHT POLYETHYLEN, AND EMULSIFIER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-06-18 | — | — | US | disclosed |