Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959629 | 0.77 | PDE10A (0.59) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL11485920 | 0.68 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL546118 | 0.68 | L3MBTL1 (0.57) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL6453590 | 0.66 | MAPT (0.43) | SMN1; SMN2L3MBTL1TDP1ALDH1A1MEN1 | |
| SCHEMBL21313236 | 0.66 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL558329 | 0.65 | LTA4H (0.56) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL23951 | 0.65 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL13510673 | 0.64 | PDE10A (0.52) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL704825 | 0.64 | PDE10A (0.59) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 | |
| SCHEMBL28486325 | 0.64 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524123-A | POLYETHERSILOXANE COPOLYMERS, HIGH MOLECULAR WEIGHT POLYETHYLEN, AND EMULSIFIER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-06-18 | — | — | US | disclosed |