Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959791 | 1.00 | POLB (0.46) | POLBTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL10987163 | 0.90 | POLB (0.46) | POLBTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL10957053 | 0.80 | POLB (0.45) | POLBTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL10957054 | 0.80 | POLB (0.45) | POLBTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL10959821 | 0.76 | ALDH1A1 (0.52) | TDP1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10959826 | 0.76 | ALDH1A1 (0.52) | TDP1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL22306362 | 0.72 | LMNA (0.43) | POLBTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL7743875 | 0.70 | ALDH1A1 (0.50) | POLBTDP1ALDH1A1MAPTUSP2 | |
| SCHEMBL7547845 | 0.70 | ALDH1A1 (0.50) | POLBTDP1ALDH1A1MAPTUSP2 | |
| SCHEMBL7542795 | 0.70 | ALDH1A1 (0.61) | POLBTDP1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088545-B1 | FUNGICIDAL CYANOPROPENOATES AND COMPOSITIONS CONTAINING THEM | FBC LIMITED (GB) | 1985-12-11 | — | — | EP | disclosed |
| US-4508659-A | 2-Cyano-3-benzylamino-2-propenoates, useful as fungicides | FBC LIMITED (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0088545-A1 | Fungicidal cyanopropenoates and compositions containing them | FBC LIMITED (GB) | 1983-09-14 | — | — | EP | disclosed |