Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 14/20 | 0.72 |
| ▸ | SLC5A2 | P31639 | 11/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10960926 | 1.00 | SLC5A1 (0.72) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL10960922 | 0.89 | SLC5A1 (0.60) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| Asebotin SCHEMBL10429626 | 0.82 | SLC5A1 (0.84) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL8109767 | 0.81 | SLC5A1 (0.85) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL10964418 | 0.78 | MEN1 (0.52) | SLC5A1SLC5A2CYP3A4CYP2C9 | |
| SCHEMBL30870414 | 0.78 | SLC5A1 (0.73) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL29452387 | 0.78 | SLC5A1 (0.70) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL3673113 | 0.78 | SLC5A1 (0.66) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL31028361 | 0.77 | SLC5A1 (0.72) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL3120891 | 0.77 | ALDH1A1 (0.80) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051819-B1 | TETRA-SUBSTITUTED BENZENE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-02-13 | — | — | EP | disclosed |