Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 7/20 | 0.80 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739866 | 1.00 | — | — | |
| SCHEMBL7622419 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL8462888 | 0.95 | — | — | |
| SCHEMBL11743476 | 0.91 | INMT (0.67) | INMTBRD4BRD2LMNAALOX15 | |
| SCHEMBL2887326 | 0.89 | — | — | |
| SCHEMBL11743467 | 0.87 | INMT (0.61) | INMTBRD4BRD2LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL11484689 | 0.86 | — | — | |
| SCHEMBL11485199 | 0.80 | INMT (0.81) | INMTBRD4BRD2 | |
| SCHEMBL19063092 | 0.74 | — | — | |
| SCHEMBL8236320 | 0.71 | INMT (0.52) | INMTBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020303-B1 | GUANIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | disclosed |
| EP-0020303-A1 | Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |