⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11484689 | 0.97 | — | — | |
| SCHEMBL7622419 | 0.92 | — | — | |
| SCHEMBL11485199 | 0.90 | INMT (0.81) | — | |
| SCHEMBL11739866 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8462888 | 0.89 | — | — | |
| SCHEMBL10960992 | 0.89 | INMT (0.80) | — | |
| SCHEMBL11743476 | 0.81 | INMT (0.67) | — | |
| SCHEMBL19063092 | 0.78 | — | — | |
| SCHEMBL11743467 | 0.78 | INMT (0.61) | — | |
| SCHEMBL8236320 | 0.69 | INMT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485851-A | A kind of preparation method and applications of 3D printing photocurable polyimide ink | 中国科学院兰州化学物理研究所 | 2019-03-19 | — | — | CN | claimed |
| EP-0724570-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011231-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G. D. SEARLE & CO. (US) | 1995-04-27 | — | — | WO | claimed |
| US-4012418-A | Process for the preparation of pyrrolidone-2 | STAMICARBON B.V. (NL) | 1977-03-15 | — | — | US | claimed |
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
| EP-3888913-A1 | MULTI-LAYERED STRUCTURES AND USES THEREOF | NIKE Innovate C.V. (US) | 2021-10-06 | — | — | EP | disclosed |
| EP-3590942-B1 | HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-06-09 | — | — | EP | disclosed |
| EP-2812440-B1 | METHOD FOR PRODUCTION OF FURANE DERIVATIVES FROM GLUCOSE | ANNIKKI GMBH (AT) | 2019-06-26 | — | — | EP | disclosed |
| CN-109485851-A | A kind of preparation method and applications of 3D printing photocurable polyimide ink | 中国科学院兰州化学物理研究所 | 2019-03-19 | — | — | CN | disclosed |
| WO-2017049068-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| WO-2015168461-A2 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | AGILENT TECHNOLOGIES, INC. (US) | 2015-11-05 | — | — | WO | disclosed |
| US-8183234-B2 | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-05-22 | — | — | US | disclosed |
| US-20070299051-A1 | Tricyclic Guanidine Derivatives as Sodium-Proton Exchange Inhibitors | NICHOLAS PIRAMAL INDIA LIMITED. (IN) | 2007-12-27 | — | — | US | disclosed |
| EP-1812420-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | Nicholas Piramal India Limited (IN) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051476-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2006-05-18 | — | — | WO | disclosed |
| US-4211867-A | ANTISECRETORY AGENTS, HYPOGLYCEMIC AGENTS, ANTIARRHYTHMIA AGENTS | MCNEIL LABORATORIES, INCORPORATED (US) | 1980-07-08 | — | — | US | disclosed |
| US-4105769-A | Inhibition of indoleamine-N-methyl transferase by 2-iminopyridines | MERCK & CO., INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4046909-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
| US-4012418-A | Process for the preparation of pyrrolidone-2 | STAMICARBON B.V. (NL) | 1977-03-15 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |